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Primary Amebic Meningoencephalitis (PAM) Guidance for Health Care Providers

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The Florida Department of Health in Pinellas County (DOH-Pinellas) would like to remind health care providers to think primary amebic meningoencephalitis, or PAM. During the summer months, swimming activity increases in the state and Florida sees the majority of PAM cases diagnosed during this time. Most people are usually infected by breathing in contaminated freshwater or soil that contains free living amebae, such as Naegleria fowleri, Balamuthia mandrillaris and Acanthamoeba species.

The attached guidance document provides information on miltefosine availability for treatment of this infection and CDC consultation services on testing, treatment, and specimen collection/shipping.

Amebic encephalitis is a reportable disease and should be immediately reported to DOH-Pinellas 24 hours a day, 7 days a week. To report a case of amebic encephalitis or for any questions pertaining to the contents of this e-mail or attached guidance, contact DOH-Pinellas at 727-824-6932.

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